Ortho Molecular Products WholeMune

Ortho Molecular Products WholeMune

WholeMune is formulated with Wellmune WGP®, the most well-researched, yeast beta-glucan ingredient available. Yeast beta-glucans are insoluble polysaccharides with immunomodulating properties, particularly in the activation of digestive tract immune cells.

Overview

A strong immune system is integral to overall health and well- being. Maintaining a strong immune system can often be a challenge in today’s world—high stress, poor diet, lack of sleep and environmental pollutants can slow down immune response. Although the mechanism of action of yeast beta- glucans is not well-understood, a study by McFarlin et al suspects that yeast beta-glucans activate the immune system by increasing T-cell activation.1 Once swallowed, immune cells in the gastrointestinal tract take up Wellmune WGP® and transport it to immune organs throughout the body. Specific immune cells called macrophages digest Wellmune WGP® into smaller fragments and slowly release them over a number of days. The fragments then bind to neutrophils (white blood cells), via complement receptor 3 (CR3). Neutrophils are the most abundant immune cells in the body, accounting for 60- 70% of all immune cells.

Wellmune WGP®

Insoluble beta-glucan has been recognized for its immune modulation properties for centuries2 and has become the subject of over 800 human clinical studies.3,4,5